Difference between revisions of "Amit Kumar Tyagi"

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|alma_mater = [[Indian Institute of Technology Roorkee]]
 
|alma_mater = [[Indian Institute of Technology Roorkee]]
 
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{{Infobox scientist
 
|name = Amit Kumar Tyagi
 
|image = Amit Kumar Tyagi.jpg
 
|image_size  = 150px
 
| caption =
 
| birth_date = Jan 1, 1960 (Public|Private)
 
| nationality = Indian
 
| Qualification: Doctoral
 
| Experties = [[Computer Technology]] [[Chemistry]], [[Medicinal Chemistry]] [[Social Worker]]
 
| work place = [[Google]]; [[Digital Equipment Corporation]] (Public|Private)
 
| alma_mater = [[University of Minnesota]], B.S. Computer Science and Engineering (1990)<br/>[[University of Washington]], Ph.D. Computer Science (1996)
 
| known_for = [[Sports]], [[Social Worker]], [[Business]]
 
}}
 
 
 
  
 
== Professional positions ==
 
== Professional positions ==

Latest revision as of 22:22, 31 July 2020

Amit Kumar Tyagi
Amit Kumar Tyagi.jpg
Alma materIndian Institute of Technology Roorkee
Scientific career
FieldsChemistry, Medicinal Chemistry Social Worker
InstitutionsJain University

Professional positions

  • Sep 2018 – Present Professor, Centre for Nano and Material Science, Jain (Deemed-to-be-University), Bangalore India
  • Feb 2014 – Aug 2018 Associate Professor, Centre for Nano and Material Science, Jain (Deemed-to-be-University), Bangalore India
  • Dec 2010 – Dec 2013 Postdoctoral Research Fellow, Centro Química Estrutural, Instituto Superior Técnico Lisboa, Portugal
  • Oct 2007 – Nov 2010 Postdoctoral Research Fellow, Centro Química Estrutural, Instituto Superior Técnico Lisboa, Portugal
  • July 2006 – Sep 2007 Dy. Manager (R&D Biochemistry), SPAN Diagnostic Ltd. Surat, Gujrat India

Academic qualifications

  • 2006 Ph.D. in Chemistry, Indian Institute of Technology Roorkee (IITR), India
  • 2002 M.Sc. in Inorganic Chemistry, Indian Institute of Technology Roorkee (IITR), India

Research Interest

My interests are in the areas of biology and fundamental chemistry with special emphasis to explore medicinal aspects of coumarin, vanadium and copper based moiety.

  • as potent anticancer agent against human breast adenocarcinoma and lung carcinoma.
  • as potent type II anti-diabetic agent: Evaluating the glucose uptake capacity of the compounds when injected to the insulin resistant human hepatocyte carcinoma cells.
  • as anti-microbial agent: Evaluation against antibiotic resistant strains of bacteria and fungi
  • as potent tuberculosis agent.
  • to study their mode of action, transport and uptake properties which can further be tested for its clinical responses.
  • to study speciation in aqueous and biological media, lipophilicity and stability in the presence of bio-macromolecules
  • Environmental Chemistry: development of a bio-adsorbent with enhanced adsorption properties

Publications

  1. Manasa Kongot, Dinesh S.Reddy, Vishal Singh, Rajan Patel, Nitin Kumar Singhal, Amit Kumar, "A manganese (II) complex tethered with S-benzyldithiocarbazate Schiff base: Synthesis, characterization, in-vitro therapeutic activity and protein interaction studies” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 231 (2020) 118123
  2. Manasa Kongot, Dinesh S.Reddy, Vishal Singh, Rajan Patel, Nitin Kumar Singhal, Amit Kumar, "Oxidovanadium(IV) and iron(III) complexes with O2N2 donor linkage as plausible antidiabetic candidates: Synthesis, structural characterizations, glucose uptake and model biological media studies” Applied Organometallic Chemistry (2019)
  3. Dinesh S.Reddy, Manasa Kongot, Vishal Singh, Neha Maurya, Rajan Patel, Nitin Kumar Singhal, Fernando Avecilla, Amit Kumar, “Coumarin tethered cyclic imides as efficacious glucose uptake agents and investigation of hit candidate to probe its binding mechanism with human serum albumin” Bioorganic Chemistry (2019) 92, 103212
  4. M. Kongot, D. Reddy, V. Singh, R. Patel, N.K. Singhal, Amit Kumar “ONS donor entwined iron(III) and cobalt(III) complexes with exemplary safety profile as potent anticancer and glucose uptake agents” New Journal of Chemistry (2019) 43, 10932-10947
  5. M.R. Maurya, B. Sarkar, Amit Kumar, N. Ribeiro, A. Miliūtė, JC. Pessoa, “New thiosemicarbazide and dithiocarbazate based oxidovanadium(IV) and dioxidovanadium(V) complexes. Reactivity and catalytic potential” New Journal of Chemistry (2019) 43, 17620-17635
  6. M Kongot, D Reddy, V Singh, R Patel, NK Singhal, Amit Kumar “Potent drug candidature of an ONS donor tethered copper (II) complex: Anticancer activity, cytotoxicity and spectroscopically approached BSA binding studies” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 212 (2019) 330-342
  7. Manasa Kongot, Neeraj Dohare, Dinesh S Reddy, Neha Pereira, Rajan Patel, Mahesh Subramanian, Amit Kumar, In vitro apoptosis-induction, antiproliferative and BSA binding studies of a oxidovanadium (V) complex, Journal of Trace Elements in Medicine and Biology 51 (2019) 176 –190.
  8. Manasa Kongot, Neeraj Dohare, Vishal Singh, Nitin Kumar Singhal, Rajan Patel, Amit Kumar, A novel biocompatible NiII tethered moiety as a glucose uptake agent and a hit against methicillin-resistant Staphylococcus aureus, Eur. J. Pharma. Sci. 123 (2018) 335 – 349.
  9. Dinesh S. Reddy, Manasa Kongot, Sandeep P. Netalkar, Mahantesh M. Kurjogi, Rakesh Kumar, Fernando Avecilla, Amit Kumar, “Synthesis and Evaluation of Novel Coumarin-Oxime Ethers as Potential Anti-tubercular Agents: Their DNA Cleavage Ability and BSA Interaction Study” Eur. J. Med. Chemistry 150 (2018) 864-875
  10. N Maurya, M ud din Parray, JK Maurya, Amit Kumar, R Patel, “Interaction of promethazine and adiphenine to human hemoglobin: A comparative spectroscopic and computational analysis” Spectrochimica Acta Part A: Mole. Biomole Spect. 199 (2018) 32–42
  11. Aparajita Shankar, Manasa Kongot, Vipin Kumar Saini, Amit Kumar, “Removal of Pentachlorophenol Pesticide from Aqueous Solutions using Modified Chitosan” Arab. J Chem. (2018) 1878-5352 https://doi.org/10.1016/j.arabjc.2018.01.016
  12. Jitendra Kumar Maurya, Abbul Bashar Khan, Neeraj Dohare, Anwar Ali, Amit Kumar, Rajan Patel “Effect of aromatic amino acids on the surface properties of 1-dodecyl-3-(4-(3-dodecylimidazolidin-1-yl)butyl)imidazolidine bromide gemini surfactant” J. Disp. Sci. Tech. (2018) 39 174-180
  13. B Aneja, M Kumari, A Azam, Amit Kumar, M Abid, R Patel “Effect of triazole‐tryptophan hybrid on the conformation stability of bovine serum albumin” Luminescence (2018) 1522-7243 https://doi.org/10.1002/bio.3435
  14. Manasa K., Neha Maurya, Neeraj Dohare, Mehraj ud din Parray, Jitendra K Maurya, Amit Kumar, Rajan Patel; “Enthalpy-driven interaction between dihydropyrimidine compound and bovine serum albumin: A spectroscopic and computational approach” J. Biomolec. Stru. Dyn. 36 (2018) 1161-1170
  15. Dash S.P, Roy S., Mohanty M., Carvalho M.F.N.N., Kuznetsov M. L., Pessoa J. C., Kumar Amit., Patil Y. P., and Dinda R., “Versatile Reactivity and Theoretical Evaluation of Monomeric and Dimeric Oxidovanadium(V) Compounds: Electrogeneration of Mixed-Valence VIVV V Complexes” Inorg. Chem. 55 (2016) 8407 – 8421.
  16. Kuntikana S., Bhat C., Kongot M., Bhat S.I., and Kumar Amit., An Expeditious Green Cascade Synthesis of 3-Arylideneaminoquinazolin-4(1H)-one Derivatives via ‘Solvent Drop Grinding’ and Their Antioxidant and DNA, Protective Studies, Chemistry Select 1 (2016) 1723 – 1728
  17. Patel R., Kumari M., Dohare N., Khan A.B., Singh P. and Kumar Amit., Binding interaction between pyrrolidinium based ionic liquid and bovine serum albumin: A spectroscopic and molecular docking insight” Biochem. Anal. Biochem. (2016), 265 , 2161-1009.1000265
  18. Bhat C and Kumar Amit., Synthesis of allokainic acid, A review Asian. J. Org. Chem, 4 (2015) 102-115.
  19. Mukherjee T., Pessoa J.C, Kumar Amit., Sarkar A.R., Formation of an unusual pyridoxal derivative: Characterization of Cu(II), Ni(II) and Zn(II) complexes and evaluation of binding to DNA and to human serum albumin, Inorg. Chim. Acta. 426 (2015) 150-159.
  20. Maurya M.R., Chaudhary N., Kumar Amit., Avecilla F., Pessoa J.C., “Polystyrene bound dioxidovanadium(V) complexes of 2-acetylpyridine derived ligands for catalytic oxidations” Inorg. Chim. Acta., 420 (2014) 24-38
  21. Maurya M.R., Haldar C., Kumar Amit., Kuznetsov M., Avecilla F. and Pessoa J.C.; “Effect of coordination sites on vanadium complexes having [VO]2+, [VO]3+ and [VO2]+ cores with hydrazones of 2,6-diformyl-4-methylphenol: Synthesis, characterization, reactivity, and catalytic potential” Dalton Trans. 42 (2013) 11941-11962
  22. Mukherjee T., Pessoa J.C., Kumar Amit., Sarkar A.R., “Synthesis, Structure, Magnetic Properties and Biological Activities of Supramolecular Copper(II) and Nickel(II) Complexes with Schiff Base Ligand Derived from Vitamin B6” Dalton Trans. 42 (2013) 2594–2607
  23. Maurya M.R., Bisht M., Chaudhary N., Kumar Amit., Avecilla F., Pessoa J.C, “Spectroscopic and structural characterization of oxidovanadium(V) mixed ligand complexes” Eur. J. Inorg. Chem., (2012) 4846–4855
  24. Maurya M.R., Haldar C., Khan A., Azam A., Salahuddin A., Kumar Amit., Pessoa J.C., “Synthesis, characterization, catalytic and antiamoebic activities of vanadium complexes of binucleating bis(dibasic tridentate ONS donor) ligand systems” Eur. J. Inorg. Chem.(2012) 2560–2577
  25. Mukherjee T., Pessoa J.C, Kumar Amit., Sarkar A.R., “Synthesis, spectroscopic characterization, insulin-enhancment, and competitive DNA binding activity of a new Zn(II) complex with a vitamin B-6 derivative-a new fluorescence probe for Zn(II)” Dalton.Trans., 41 (17) (2012) 5260–5271
  26. Maurya M.R, Sani P., Kumar Amit., Pessoa J.C, “Oxidovanadium(IV)Complexes of Tetradentate Ligands Encapsulated in Zeolite-Y as Catalysts for the Oxidation of Styrene, Cyclohexene and Methyl Phenyl Sulfide” Eur. J. Inorg. Chem. 31 (2011) 4846–4861
  27. Maurya M.R., Kumar Amit., Pessoa J.C., “Vanadium complexes immobilized on solid supports and their use as catalysts for oxidation and functionalization of alkanes and alkenes” Coord. Chem. Rev. 255 (2011) 2315–2344 4361
  28. Mukherjee T., Pessoa J.C, Kumar Amit., Sarkar A.R, “Oxidovanadium(IV) Schiff Base Complex Derived from Vitamin B-6: Synthesis, Characterization, and Insulin Enhancing Properties” Inorg. Chem., 50 (2011) 4349–4361
  29. Maurya M.R, Bisht M., Kumar Amit., Kuznetsov M.L., Avecilla F., Pessoa J.C., “Models of vanadate-dependent haloperoxidases: Synthesis, characterization, reactivity and catalytic activity of oxidovanadium(IV), oxidovanadium(V) and dioxidovanadium(V) complexes of benzimidazole modified ligands” Dalton.Trans., 6968–6983 (2011)
  30. Maurya M.R., Arya A., Kumar Amit., Avecilla F., Pessoa J.C., “Polymer-Bound Oxidovanadium(IV) and Dioxidovanadium(V) Complexes As Catalysts for the Oxidative Desulfurization of Model Fuel Diesel” Inorg. Chem., 49 (2010)6586–6600
  31. Maurya M.R, Khan A., Azam A., Ranjan S., Mondal N., Kumar Amit., Avecilla F., Pessoa J.C., “Vanadium complexes having [VO]2+ and [VO2]+ cores with binucleating dibasic tetradentate ligands: Synthesis, characterization, catalytic and antiamoebic activities” Dalton.Trans., (2010) 1345–1360
  32. Maurya M.R., Khan A., Azam A., Kumar Amit., Ranjan S., Pessoa J.C., “Dinuclear oxidovanadium(IV) and dioxidovanadium(V) complexes of 5, 5’-methylenebis(dibasic tridentate) ligands: synthesis, spectral characterisation, reactivity, catalytic and antiamoebic activities” Eur.J. Inorg. Chem. 35 (2009) 5377–5390
  33. Maurya M.R., Arya A., Kumar Amit., Pessoa J.C, “Polymer-bound oxidovanadium(IV) and dioxidovanadium(V) complexes: synthesis, characterization and catalytic application for the hydroamination of styrene and vinyl pyridine” Dalton.Trans., (2009) 9555–9566
  34. Maurya M.R., Arya A, Kumar Amit., Pessoa J.C, “Polystyrene bound oxidovanadium(IV) and dioxidovanadium(V) complexes of histamine derived ligand for the oxidation of methyl phenyl sulfide, diphenyl sulfide and benzoin” Dalton.Trans., (2009) 2185–2195
  35. Maurya M.R., Kumar M., Kumar Amit., Pessoa J.C, “Oxidation of p-chlorotoluene and cyclohexene catalysed by polymer-anchored oxovanadium(IV) and copper(II) complexes of amino acid derived tridentate ligands” Dalton.Trans., (2008) 4220–4232
  36. Maurya M.R., Kumar Amit., Ebel M., Rehder D., “Synthesis, characterization,reactivity and catalytic potential of model vanadium (IV,V) complexes with benzimidazole derived ONN donor ligands” Inorg. Chem., 45 (2006) 5924 –5937
  37. Maurya M.R, Kumar Amit., “Oxovanadium(IV) based coordination polymersand their catalytic potentials for the oxidation of styrene, cyclohexene and trans stilbene” J. Mol. Catal. A: Chem., 250 (2006) 190–198
  38. Maurya M.R., Kumar Amit., Abid M., Azam A., “Dioxovanadium(V) and μ-oxo bis[oxovanadium(V)] complexes contaning thiosemicarbazone based ONS donor set and antiamoebic activity” Inorg. Chim. Acta., 359 (2006) 2439–2447
  39. Maurya M.R., Kumar Amit., Bhat A.R., Azam A., Bader C., Rehder D., “Dioxo and oxovanadium(V) complexes of thiohydrazones ONS donor ligands: Synthesis, characterization, reactivity, and antiamoebic activity” Inorg. Chem., 45 (2006) 1260–1269
  40. Maurya M.R., Kumar Amit., Manikandan P., Chand S., “Synthesis, characterisation and catalytic potential of oxovanadium(IV) based coordination polymers having a bridging methylene group” Appl. Catal. A: Gen 277 (2004) 45–53
  41. Maurya M.R., Saklani H., Kumar Amit., Chand S., “Dioxovanadium(V) complexes of dibasic tridentate ligands encapsulated in zeolite-Y for the liquid phase catalytic hydroxylation of phenol using H2O2 as oxidant” Catal. Lett. 93 (2004) 121–127

Publication in national science magazine

Book published

  • Amit Kumar; Role of Vanadium Complexes in Biological Systems & Oxidation Reactions, LAP Lambert Academic Publishing Germany 2011. ISBN 978-3-8465-4955-1.

Awards, Honors and Recognitions

  • 2018 Best paper award in Recent Advances in Chemical and Material Sciences (RACMS) at Jain (Deemed-to-be-University) Bangalore India
  • 2017 Best paper award in ‘Green Chemistry & Nanotechnology- Opportunities and Challenges (GCNOC), St. Aloysius College, Mangalore, India
  • 2017 Best paper award in ‘New Trends in Applied Chemistry (NTAC)’, Kochi, India
  • 2016 Prof. B. C. Haldar Memorial Award’ by Indian Chemical Society in the ‘Annual Convention of Chemists’, GITAM University Vizag, India for the best paper in Inorganic Chemistry section.
  • 2015 Best poster award in ‘Interdisciplinary approaches in Chemical Sciences (IACS), JMI New Delhi, India
  • 2014 Traveling grant by SERB-DST to attend 9th International Vanadium Symposium, in Padova, Italy from June 29th -July 2nd, 2014
  • 2013 Postdoctoral Fellowship by Foundation of Science & Technology (FCT) Portugal
  • 2012 Three month research grant by Foundation of Science & Technology (FCT) Portugal for collaborative research between IST Lisbon Portugal – IIT Roorkee India
  • 2012 Traveling grant by Foundation of Science & Technology (FCT) Portugal to attend The XXV International Conference on Organometallic Chemistry (XXV ICOMC, Lisbon, Sept. 2-7) 2012
  • 2011 Three month research grant by Foundation of Science & Technology (FCT) Portugal for collaborative research between IST Lisbon Portugal – IIT Roorkee India
  • 2010 Three month research grant by Foundation of Science & Technology (FCT) Portugal for collaborative research between IST Lisbon Portugal – IIT Roorkee India
  • 2010 Postdoctoral Fellowship by Foundation of Science & Technology (FCT) Portugal
  • 2009 Three month research grant by Foundation of Science & Technology (FCT) Portugal for collaborative research between IST Lisbon Portugal – IIT Roorkee India
  • 2009 Traveling grant by Foundation of Science & Technology (FCT) Portugal to attend The 10th Netherlands Catalysis and Chemistry Conference March 2-4, * 2009, Noordwijkerhout, the Netherlands
  • 2009 Traveling grant by Foundation of Science & Technology (FCT) Portugal to attend 8th Inorganic Chemistry Conference, 16 & 17 October 2009, Curia, Portugal.
  • 2008 Three month research grant by Foundation of Science & Technology (FCT) Portugal for collaborative research between IST Lisbon Portugal – IIT Roorkee India
  • 2007 Postdoctoral Fellowship by Foundation of Science & Technology (FCT) Portugal
  • 2004 Prof. B.C. Haldar Memorial Award 2004 – 41stAnnual Convention of Chemists (Indian Chemical Society) at University of Delhi
  • 2003 Indian Chemical Society Award 2003 – 40st Annual Convention of Chemists (Indian Chemical Society) at Bundelkhand University, Jhansi
  • 2002 Institute Fellowship by Ministry of Human Resource Development (MHRD), Govt. of India for Ph.D. program of Indian Institute of Technology Roorkee
  • 2004 Selected for Shyama Prasad Mukherjee Fellowship Test, (JRF) Net awardees who secured top 20% position at all India level on the basis of Joint CSIR-UGC JRF)
  • 2003 Qualified CSIR-UGC National Eligibility Test (NET)
  • 2002 Qualified CSIR-UGC National Eligibility Test (NET)
  • 2002 Graduate Aptitude Test in Engineering (GATE) (95.17 percentile) (All India Rank 121)
  • 2001 Qualified CSIR-UGC National Eligibility Test (NET)

References